Fallout 4
So, yeah, it's more Fallout. Honestly, I find the sense of (perhaps somewhat grisly) humor that seemed to be woven into the earlier games to be weaker. Otherwise, it's Fallout 3 + 10 years of in-world time, in a slightly different location. There are a lot of references to the previous (number-wise) game. In fact, a one-off little quest in 3 where a person from the mysterious "Institute" sends you off to find a synthetic person has become a core conceit of 4. The combat mechanics are a little better than before. VATS only slows action greatly rather than totally pausing it - which has ups and downs. The non-VATS shooting, though, is much more precise and player-skill-based. I understand they consulted with another studio to help with that. Exploration is about the same as before. There's the additional aspect of being able to set up and maintain settlements (Farmville Fallout?), which is... a bit clunky, but does add something. I'm still not sure if the grea